I am not using an nVidia card, so I don't think it's nVidia drivers alone. I am using an AMD Radeon HD 6950 and the latest 12.4 Catalyst Control Suite. Here's my setup:
Motherboard: Asus Z77 Sabertooth (BIOS 1015)
Processor: Intel i5-2500k
Memory: Corsair Vengeance 1600MHz - 16GB (2x8GB)
GPU: AMD Radeon HD 6950 (Catalyst Suite 12.4)
Storage: Crucial m4 128GB SSD and Western Digital Caviar Black 640GB SATA HDD
OS: Windows 7 Professional 64-bit
I will try fully draining the motherboard's power today. I shut off the power supply switch every night, but I'll unplug it also and let it drain for a bit. I also haven't done any overclocking yet, so my BIOS settings should be at default, but I'll set them back to default and check that out also.
Over on
Overlock.net's z77 owners thread there are a number of people with this shut down problem.