stripped screw on z270i itx

[JeddiMaster26]

i was planning to add m.2 nvme but when i was about to pull out the screw the 2nd one got stripped. i thought i was the only
one having this problem but i saw few people complaining about it. ended up damaging the screw just to pull out the heatsink. only one screw was
holding it. expensive mobo but cheap screws

[xeromist]

It might not be as pretty but I think you should be able to run without the cover. As long as the drive itself is secured and there is some airflow in the case you should be fine.