I'm surpsiesd you managed to contain it somehow or get rid of it. I tried with 2 power supplies already and same whine coming from the motherboard. Waiting on a possible bios patch for it.

Well, my case has a bit of soundproof and it definitely helps, I can recommend it as long as you have good airflow but the whining it's certainly there  Now that they got the boot times right, they haven't published any bios updates for a while. I s...

You know if you have installed version 1414 beta of BIOS then it will not be the 'most stable'. Have a look again, I see your board has version 1616 as well available which you can flash via USB. I would do this as a first step.

Does anyone know if Asus is aware of this? I believe OP tagged this incorrectly as X670 as the details are B650E. I think it'd be worth following up in my case as the issue matches 100% what OP is saying and I also have the AMD Ryzen 7 7700X. I have ...

Oh, on my Strix B650E-E Gaming Wifi with the same problem. I was thinking this was my AIO but I unplugged it and the whine continues. I have unplugged everything including my GPU and still there. It's really annoying. I can try setting a fixed voltag...