ASUS already offers lots of laptops with Intel CPUs and NVIDIA GPUs lol.
No laptops are built with desktop CPUs. Not by ASUS, not by anyone else.
Laptop motherboards aren't as standardized as desktop motherboards, they're somewhat consistent in terms of form-factor but the manufacturers have a lot of flexibility. They basically design the motherboard and daughterboards and other PCBs along with the chassis everything fits inside, they can add/remove ports and slots and features just like they do across different desktop motherboard models.
Intel mobile CPUs are sometimes soldered (permanently) in place on board, and sometimes use some variety of "socket". But either way they are not physically or electrically compatible with Intel desktop CPUs. They might have similar Intel model numbers and specs to their desktop counterparts but they're aren't at all interchangeable. They also tend to selected/binned with consideration towards power efficiencies.
Laptop GPUs are often
MXM cards. They can be swapped or upgraded. But there are numerous little proprietary differences and issues between them and the motherboards they plug into. It's often easier to just leave them in place and treat them as "permanent" hardware.
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