If you right-click on Rotation Desktop in "Control Panel - Uninstall a program", does the popup menu display a "Repair" option? If it does and you choose it, does it resolve your issue?
Alternatively, you could try using Windows System Restore to restore your system to an earlier time, hopefully when the Rotation Desktop worked without issue.
I believe the Rotation Desktop also depends on other ASUS apps, like "GameFast" for instance. Have you uninstalled any of the ASUS apps?
G74SX-A1 - stock hardware - BIOS 202 - 2nd Monitor VISIO VF551XVT