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Rog strix z490-f gaming which m.2 slot

DR3WST3R
Level 7
howdy, does it matter which m.2 slot to use, got an nvme 250 gig for windows and an nvme 2TB for games, or does it not matter, all help well appreciated.
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GettnBetter
Level 9
On mine with a single graphics card, the slot closest to the CPU, under the primary PEI-e slot runs on average 5c hotter than the other.

All m.2 storage cards will throttle performance due to heat, look up the thermal thresholds for each m.2 device and place the one that has higher tolerances in the hotter slot.

I never understood why mobo designers place these M.2's in what seems to be the hottest locations on the motherboards right under the GPU heatsink fins.