Water cool the chip, and you can put ram with heatspreaders that stick out of the case, personally I water cool chip, and then get a active ram cooler, ZALMAN makes excelent cooling solutions for ram, also Corsair Dominator Cooler is a good option, dial speed down and you should have silent and cold rig. I like water because it doesn't put any stress on board and takes less space.
My ROG: MOBO: ASUS Crosshair V Formula | CPU: AMD 1100T Black Edition (O/C 4.125 GHz) | RAM: G.Skill Ripjaws 1600 4x4 GB (PC12800 842 MHz) | PSU: Rosewill 1000W 80+ Bronse
GPU: 2xEVGA GTX 560Ti 2GB VRAM | Primary HDD: Samsung 470S 128 GB SSD | Secondary HDD's: 3x WD Caviar Green 2TB Non Raid | ODD: Samsung BD-R/DVD-RW
Cooling: CPU: Corsair H5O with Push Pull Scythe Slipstream fans | Rest: GELID Ultra quiet closed loop fans. | Control: Zalman ZM-MFC2