Hi,
i also have the Prime X370 pro board with a ryzen 1700x (running at constant 3800 mhz).
I got 2 Corsair DDR4 3200 DIMMS installed (16 GB total), using slot 2 and 4.
They were running on D.O.C.P. 3200 for a while, until i experienced random crashes in PUBG. After these crashes i updated the BIOS to version 0805.
From that point on every POST failed, resetting the BIOS to failsafe settings.
The only thing that worked is reducing the DIMM's speed to D.O.C.P. 3000.
The BIOS is still recognizing the DIMM's as 2133 mhz DIMM's but they running like a charm on 3000 mhz.
There is something wrong with this BIOS version if you ask me, but than again, i was already having stability problems on 3200 mhz before this BIOS.
So i guess i will stick with the 3000 mhz for now.
Lots of tekst but the answer to your question is: The Prime X370 pro board is very much able to support higher frequencys than 2666 on multiple DIMM's.