i had the similiar problem with my Maximus V Gene on 2500K GTX560 TI Top Corsair Vengence ...
my problem was after i install Adobe X Reader and after i exit BF3 .. then my mouse frooze and some to my keyboard
i tried to restart = once in win7 64, both freeze ...
i went to bios, everthing is ok, i can move with my keyboard and mouse
back to win7 ... freeze ..
so i reset bios ... same ... bios ok .. win7 freeze ...
i went to bios to load default setting ...
reboot .... inside bios OK .. win7 freeze ..
so i went to win7 safe mode ... everthing ok .. i cannot uninstall win7 ..
so i replug all my asmedia usb 3.0 port and try plugging to asus usb3.0 port .. still same
tried every configuration of my mouse n keyboard on all asmedia and asus 3.0 port
finally ... i use my USD10 bucks cheap logitech mouse connected to my front (USB2.0) port ..
and it works ...
i reinstall asmedia and asus 3.0 mouse driver and now ... so far .. it's WORKING BACK TO NORMAL
Hopes this help guys ...
i5-2500k @ 4.7ghz @ 1.352V (Bios) 1.352V (CPU-Z)
Asus ROG Maximus V Gene Z77 Bios 0701
Asus ENGTX560 Ti DC2 TOP/G/2DI/1GD5 @ 1042/950mhz
Corsair Force Series3 120GB SATA 3 6Gb/s SSD
Win7 Ultimate SP1 x86 | Viewsonic VA1912WB
Corsair Vengeance 8GB DDR3 1600MHZ | Corsair Carbide 300R
Razer Imperator Battlefield 3 | Razer Copperhead
Razer BlackWidow Ultimate Battlefield 3
Razer ExactMat Xcontrol | Razer Scarab Battlefield 3
Noctua NH-U9B SE2, NF-S12B FLX x2, NF-P12 x2, NF-P14-FLX x2