I'm not a gamer per say, but I purchased and built a gamers rig (as a DAW) solely for the use of playback..
Here's a few tips..
Be sure Processor Scheduling in Windows is set to "Background services"
Ideally, you want to achieve 1.0GB maximum Memory utilization in Windows/at idle.. This is to insure you have very little running at startup and in the background. I find that 1.0GB utilization (or less) has a profound effect on the quality of audio playback. One very high memory utilization app is Windows Defender, so try: Control Panel -> Windows Defender -> uncheck "real-time" -> administrator -> uncheck "use program". Again, a slight improvement in audio playback.
If your familiar with Windows Registry and comfortable with making changes, search for "dec35" and find an entry called "Attributes" and change the data value from 1 to 0. This is "Core Parking" value(s) and would turn Core Parking off.
The jury is still out on this one..
Right click on your hard drive(s) -> go to properties -> uncheck "Allow files on this drive to have contents indexed
in addition to file properties".
Now as for the BIOS, I could post my BIOS settings here.. Through many years of testing BIOS relationships with audio cards, this is what I have discovered. There seems to be BIOS settings/Audio Card "sweet" spots and they are different for each and every BIOS/MOBO/Audio Card combination. But one thing I have found that they all share in common is aggressive overclocking eventually begins to degrade the audio playback.. Slight distortion seems to occur at the higher frequencies during transients (like symbols, upper midrange etc..) as a result of aggressive timings. Mediocre to moderate timing, however, seems to be where the audio playback sweet spots are found and the wider frequency ranges are present.
I'll post more as they come to mind (I do have a DAW list/guidelines) and post them here along with my current BIOS settings.