FWIW, larger modules means fewer modules and generally means less work for the memory controller. Of course variance in the timing, voltage, and density can also impact compatibility between modules but as a general rule I'd take 4x8GB over 8x4GB unless I knew the chip density would work better with my CPU. Intel seems less impacted by densities than AMD so I'd go with fewer modules for a few extra bucks.
A bus station is where a bus stops. A train station is where a train stops. On my desk, I have a work station…