From a jayz2cents video, he said with the latest mobo's using the dimm.2 you have to make sure you put your nvme ssd in the slot that has the heatsink attached. there are 2 sides. Also if you use 2 nvme ssd's in the dimm.2 you have to use pretty much the same nvme's so if one is a 2gig 4.0 ssd and the other is a 1 gig 3.0 the mobo can have issues with that, and run only at the 3.0 speeds. So just put the 2nd ssd in a different slot on the board itself. As far as unscrewing it, just use a hair dryer and heat the thing up. Or if a hair dryer/ heat gun isnt available put it in an oven at its lowest setting for a minute or 2 until its warm but not HOT. Also screwing it back together once the card is in, you just have to put alot of pressure in the middle with 1 hand and with the other put the screws in. Slightly tighten them, 1 then the 2 then 1 then the 2nd, until they are both screwed in. It might not be screwed in all the way, but thats ok.
Here is the video, it starts at 4:45 and its a amd board, so not sure if that dimm.2 is exactly the same. But im guessing it is.
https://youtu.be/GgOWUuS5ras