That version of the ME firmware from 2021 was flawed and prior releases contain security concerns. The latest ME resolves this issue. The ME firmware listed on the ASUS support page is not useful, not sure why it's even there. ME 22.214.171.1248 [13/02/2023] works. Install that inside a healthy version of Windows, shutdown, remove power. Boot into BIOS, update the BIOS to the latest, reboot, restore any needed settings or re-do OC and fan profiles and all will be well. The ME itself is purely an Intel thing, a micro Linux OS embedded in the CPU firmware that does mysterious essential things.