The 16TB limit is for the normal (most common/ default) allocation size of 4K (which should still be supported). Anyway, you can use a larger allocation size from 8K to 2MB (allowing 8 petaBytes). The biggest issue with such large hard drives is that I suspect it's using shingled storage (SMR) which means slower write speeds (not by a massive amount). The drives and type of RAID used all depends on what you're doing. In this PC I have two 4TB drives in RAID0(striping) as speed and capacity are more important than safety/ reliability. Just try not to put all your eggs into one basket.
TooLoud wrote:Honestly took a loooong time to save up for this huge disk...
Just make sure you backup your backups, with important stuff elsewhere.
Out of curiosity, what OS was it that killed your data? I know Windows wouldn't do that is it's destructive (insert unsupported filesystem and it will delete your data, not a feature most would want).