I'd greatly appreciate it if I could get a yes or no answer to my question. If yes, then is there something that needs to be done in order to make it happen? FYI, I have no RGB in my case and I got the Rog Ryujin II 360 that has the Noctua fans (No RGB).
Not positive -- but I think power for the pump comes from the controller box, while usb2 connection is strictly for data and control of the display. I don't think the usb2 power is used for the pump (but I could be wrong).
You don't have to connect the fans to the controller. I have used it with the radiator fans connected to the motherboard, and everything worked fine. But the control box was still in place, and the cooler was still connected to it (in addition to usb2).