There are some RGB LEDs on the right edge of the MB.

These LEDs can be controlled by Armoury Crate software together with other LEDs on the MB as a whole device, but it cannot be recognized and controlled by Aura Creator.
To be specific, the MB could be shown in Aura Creator's PC Components section as a whole device, but the RGB LEDs on the right edge of the MB could not be lighted and could only stay completely off, only LEDs in the cover of the I/O ports and South Bridge (the ROG logo) could be lighted and controlled by Aura Creator.
It was an odd issue since the R6E motherboard was not a new product, it still could not work properly with ASUS's own software.