I have not read most of these threads so I am assuming some of you guys might have figured a good config. that works for you.
The version bundled with my cards was not the most recent so I went to the ASUS site and downloaded the most recent version. 2.0.5.3
I set my fans to 80% (quite loud) , I max out the GPU voltage (1250) as well as the GPU clock (1125), I basically max out the memory clock to around 6250, the memory voltage i keep lower around 1625.
Granted this is pushing it, and I don't do it all the time, I get phenomenal results. I also have my CPU overclocked as well, however, I keep the ram speed real low so it doesn't tax the CPU. I have an X79 Rampage IV.
My two cents
Rampage IV
Intel 3960 @ 5.1 24/7
32gb G Skill Ripjawas @2400 MHZ (F3-17000CL11Q2-64GBZLD)
Asus HD 7970's x3 (Swiftech Kimodo Water Blocks)
Cosmos II (10 LED Fans w-built in fan controller)
Corsair AX 1200 PSU
Cusrom Water; Chipset/CPU/Cards/ETC
All Votex PWM Fans (German Engineered); Best I have ever used