So I finally got this beta installed. Took most of Saturday to get it up and running with the 0606 Prime Z370-A bios update (with the microcode patch) and Windows Meltdown patch.
What finally worked for me was clicking the "unblock" checkbox on the .ZIP file for the latest ASUS Aura, which then went through and installed. It was able to install a version of the ASUS COM Service that would actually run. Once that was in (after disabling Windows Defender Active Protection and putting in exclusion in for it as it kept restarting on it's own), then I could install AI Suite 3 beta 3.00.10.
Only have a couple of problems remaining... When AI Suite launches with the OS, I get a "Cannot open AsIO.sys !! (2)" message from the PE Updater program. I've since set it to run as administrator, so we'll see if that does it on next boot. Also when using AS Power Bar widget, I get a error stating: "Assertion failed: index < Count(), file src\asus\Sensor.cpp, line 1700".
So for now I've disabled the AS Power Bar and just control fans through Fan Xpert using the AI Suite system tray. If I can't get the PE Updater Application error fixed, I'll probably just uninstall that feature.
With that said, any help with either issue would be greatly appreciated.