Make sure you have installed the latest AMD chipset drivers (that is not the ones supplied by windows or the ones on ASUS website and yes they are older) The ones you need are from AMD, here
https://www.amd.com/en/support/chipsets/amd-socket-am4/x570In regards to setup of TPM using BIOS, it is kinda related to the correct setup of your Nvme drive, so I have just given that detail and you can work it out, if you have got it set up correctly. Best way to check is to use HWinfo
https://www.hwinfo.com/download/ and If done correctly on the summary page towards bottom right, Operating System UEFI Boot will be in green and Secure Boot will be in green (either in grey means you have done something wrong.)
Here is the procedure for install of windows on nvme drive.
1 - Make sure you unplug all SATA and USB drives, the M.2 drive has to be the only drive installed.
2 - Go into the bios, under the boot tab there is an option for CSM, make sure it is disabled.
3 - Click on secure boot option below and make sure it is set to other OS, Not windows UEFI.
4 - Click on key management and clear secure boot keys.
5 - Insert a USB memory stick with a UEFI bootable ISO of Windows 10 on it.
6 - Press F10 to save, exit and reboot.
7 - Windows will now start installing to your NVME drive as it has its own NVME driver built in.
8 - When the PC reboots hit F2 to go back into the BIOS, you will see under boot priority that Windows boot manager now lists your NVME drive.
9 - Click on secure boot again but now set it to Windows UEFI mode.
10 - Click on key management and install default secure boot keys <- this is the step that sets up BIOS TPM
11 – Press F10 to save and exit and windows will finish the installation.
Generally it is really important to install Nvme exactly as described above. If you ever have windows 10 issues or decide to dual boot your system and for example have skip step 1, you will find just how annoying windows 10 boot loader can be etc and for each point there is reason why you should do it this way.
Hope you find this of help.