UEFI 2501 has restored mouse function in UEFI for me.
I believe Ryzen Master does not use ASUS WMI. This can cause Super IO chip to go whacko and lose PWM.
I have used multiple instances of CPU-Z, concurrently with single instance each of HWINFO, AIDA64 and ASUS TurboV Core v1.02.02, encountered no issues. The moment I leave Ryzen Master open for a while with these apps open I lose PWM on fan header CHA_FAN2, restulting in no fans spin as and H_AMP goes to max, resulting in DDC pump at max.
SIV can show which apps are using SMBus locking, must check RM with it.
On the rise and fall of the clock cycle...